对羟基苯乙酸铜(Ⅱ)、锌(Ⅱ)配位聚合物的合成、晶体结构及与DNA作用

摘要

合成了两种过渡金属配合物[M(HPAA)(phen)2]HPAA· 7H2O(M=Zn,1;Cu,2;HPAAˉ=对羟基苯乙酸根;phen=1,10-邻菲哕啉),并通过元素分析、红外光谱、热重分析对其进行表征,用单晶X-射线衍射方法测定了配合物的晶体结构.结构分析显示,两种配合物属于异质同晶型,不对称单元都是由1个金属离子,2个对羟基苯乙酸根离子,2个邻菲哕啉分子和7个游离的水分子组成的,其中有1个对羟基苯乙酸根离子未参与配位.每个金属离子的配位数为6,处于扭曲的八面体配位环境中.另外,用荧光光谱法研究了两种配合物与DNA之间的相互作用.%Two transition metal complexes [M(HPAA)(phen)2]HPAA·7H2O(M=Zn, 1; Cu, 2; HPAA-=4-hydroxy-phenylacetic acid anion; phen=l,10-phenanthroline) were sythesized and characterized by elemental analysis, IR and TG-DTG. Their crystal structures were determined by single crystal X-ray diffraction method. The crystal structure anlysis reveals two complexes belong to isomorphism, and the asymmetric unit contains one metal ion, two 4-hydroxyphenylacetic acid anions and seven free water molecules, one of acid anions is not coordinated with the metal ion. The metal ion is six-coordinated and involved in a distorted octahedral coordination geometry. In addition, the interaction of complexes with DNA were also studied by ethidium bromide (EB) fluorescence spectroscopy. CCDC: 729804, 1; 729805, 2.