目的：探讨历节病组方规律。方法收集《中医方剂大辞典》中治疗历节病的所有方剂，基于中医传承辅助系统(V1.1)构建数据库，采用关联规则和熵聚类的方法，分析历节病用药频次、组方规律和新方组成。结果对筛选出的187首方剂进行分析，使用频次≥14次的药物有42味，以当归为核心药物，演化得到3～4味核心组合69组、新处方6首。结论历节病组方规律和聚类新处方的分析显示，治疗历节病以调肝养脾、补益肝肾法为主。%Objective To analyze the composing principles of the prescriptions for Lijie disease by using The Prescription of Traditional Chinese Medicine Dictionary. Methods The prescriptions for Lijie disease in the book of The Prescription of Traditional Chinese Medicine Dictionary were collected. Database was established by using TCM Inheritance Support System (V1.1). Medicine using frequency, composing principles, and composition of new medicine were analyzed through association rules and entropy clustering method. Results Based on the analysis on 187 cases of prescriptions, 42 Chinese herbal medicines were with the frequency of 42 times and Angelicae Sinensis Radix was the core herbal medicine. 69 core combinations with three to four herbal medicines and 6 new prescriptions were obtained through evolution. Conclusion According to the analysis of composing principles and clustering new prescriptions of Lijie disease, the treatment for Lijie disease is toning liver and spleen, and nourishing liver and kidney.
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