目的：分析《中华人民共和国卫生部药品标准·中药成方制剂》(以下简称《中药部颁标准》)含黄芪方剂组方规律，为临床应用及新药研发提供参考。方法基于中医传承辅助系统(V2.0)构建数据库，使用关联规则、改进的互信息法等数据挖掘方法，分析含黄芪方剂主治疾病、证候规律及常用配伍组合。结果通过对446首含黄芪方剂的分析，获取黄芪常用药物组合16组，主治疾病18种。基于黄芪的主治疾病，选择“不寐”“虚劳”“眩晕”进行对比分析，得出黄芪在治疗不同疾病时用药规律和配伍特点。结论《中药部颁标准》中含黄芪方剂所用药物多有气血双补功效，用药较为集中，组方清晰；用药规律反映了黄芪治疗不同疾病时的配伍特点，符合多功效中药的临床使用现状。%Objective To analyze the composing principles of Astragali Radix in Drug Standard of Ministry of Public Health of the People’s Republic of China-TCM Prescription Preparation;To provide references for clinical application and research and development of new medicine. Methods Traditional Chinese Medicine Inheritance Support System (V2.0) was used to establish database. Data mining methods, such as association rules, improved mutual information method, were used to analyze the diseases, syndrome rules, and common composing combinations of prescriptions containing Astragali Radix. Results Through analysis on the 446 cases of prescriptions containing Astragali Radix, 16 core medicine combinations and 18 diseases were discovered. Then, based on the 18 diseases, insomnia, consumptive disease and vertigo were chosen to make comparative analysis, the medicine using regularity and compatibility features of Astragali Radix in different diseases were disclosed. Conclusion Herbal medicines used frequently in prescriptions containing Astragali Radix could tonify qi and nourish blood. The medicine using is relatively concentrated, and the composition is clear. The composing principles reflect the compatibility features of Astragali Radix in treating different diseases, which are in accordance with the clinical application of multiple-efficacy Chinese medicine.
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