Objective To analyze the characteristic changes of trace elements from Hedysari Radix in different months;To provide references for the choice of the best harvest periods. Methods Trace elements of Hedysari Radix from different months (June, July, August, September, October and November) were determined by atomic absorption spectroscopy and analyzed by single factors analysis of variance, correlation analysis, cluster analysis and factors analysis. Results There was obvious significance between the contents of Cu and Co (P<0.05), and there was obvious significance among the contents of Fe, Ca, Mn, Zn, Mg, Cr, Na, Li, Ni and K (P<0.01). The results of correlation analysis showed that months had positive correlation with Cu, had a negative correlation with Fe, Na, Mn, Cr and Li contents, and had significantly negative correlation with Ca, Mg contents. Mn, Cr, Ni, K and Na were the characteristics of trace elements from Hedysari Radix in different months. The different months samples could be divided into two categories of June, July, August, September samples (Ⅰ) and October, November samples (Ⅱ). Conclusion There is close relationship between the contents of trace elements from Hedysari Radix and months. The information and metabolic patterns of trace elements from Hedysari Radix in June, July, August, September (immature) samples are close or similar;the information of trace elements in October, November (nearly mature or maturing) samples are close or similar. Study on harvest times of Hedysari Radix by trace element as an indicator is with certain rationality.%目的：分析不同月份红芪中12种微量元素含量的变化特征，为红芪最佳采收期的选择提供参考依据。方法收集不同月份（6、7、8、9、10、11月）红芪样品，采用原子吸收光谱法测定其微量元素含量，并进行单因素方差分析、相关性分析、聚类分析及因子分析。结果不同月份红芪中铜、钴元素含量存在显著差异（P＜0.05），铁、钙、锰、锌、镁、铬、钠、锂、镍、钾元素含量存在极显著差异（P＜0.01）；铜元素含量与月份之间存在显著正相关关系，铁、钠、锰、铬、锂元素含量与月份之间存在显著负相关关系，钙、镁元素含量与月份之间存在极显著负相关关系；锰、铬、镍、钾、钠是不同时期红芪的特征性微量元素；不同时期样品聚为2类，6、7、8、9月样品聚为第一类（Ⅰ类），10、11月样品聚为第二类（Ⅱ类）。结论红芪中微量元素与月份的关系密切；6、7、8、9月（未成熟期）红芪中微量元素信息较为接近或代谢模式相似，10、11月（近成熟期或成熟期）红芪中微量元素信息较为接近；以微量元素为指标研究红芪的采收期具有一定的合理性。
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