生殖激素与男性不育症患者精子形态的相关性分析

摘要

Objectives:To explore reproductive hormones and sperm morphology of infertile men and to explore the correlation between them.Methods:From August 2008 to August 2012,600 infertile men aged from 25 to 45 were included in our study.Based on the results of sperm morphology analyses,the 600 infertile men were randomly divided into three groups,200 in each group.Results:The levels of serum free testosterone and bioactive testosterone were the only differences in statistics between the first group and the third group.The levels of serum FT and BioT were positively correlated with the percentage of morphologically normal sperm (P ＜0.05).Conclusion:The higher the levels of serum FT and BioT are,the higher the percentage of morphologically normal sperm is,which suggests positive correlation exists between reproductive hormones and sperm morphology in infertile men.%目的:研究生殖激素与男性不育症患者精子形态,探讨两者的相关性.方法:对象为2008年8月至2012年我院600例男性不育症患者,根据正常形态精子所占比例大小分为三个组,每组200例.结果:三组患者血清游离睾酮(free testosteron,FT)水平与生物活性睾酮(bioavailable testosterone,Bio-T)水平,均只有在第1组与第3组之间存在统计学的差异.另外,血清FT、Bio-T水平与正常形态精子百分率之间均存在正相关(P＜0.05).结论:男性不育症患者血清FT和Bio-T水平越高,则正常形态精子百分率越高,提示生殖激素与男性不育症患者精子形态存在着相关性.