目的 评估丙型肝炎教育对中国农村慢性丙型肝炎(CHC)患者疾病知识和抗病毒治疗接受程度的影响. 方法 河北省某县CHC项目的农村患者接受HCV教育,包括医生给予讲座和随后进行的互动式讨论,并完成教育前后测试. 结果 总共纳入151例CHC患者.平均年龄为57.3岁,50.3％为男性,51.0％患者的受教育程度为小学或文盲,76.2％的家庭月收入低于3 000元.98.0％的患者将其基线丙型肝炎知识定义为“无”或“只有一点”.多因素分析显示,年龄和家庭收入与基线知识总分相关.教育后,患者知识总分的平均分(范围:0～28分)从13.1升至23.0(P＜ 0.001),题目回答正确患者的平均百分比从46.8％升至82.1％ (P＜ 0.001),患者对抗病毒治疗的接受程度从33.9％升至65.6％(P＜0.001).结论 虽然中国农村患者的受教育程度较低,按患者选择的方式进行的丙型肝炎教育可以显著改善患者的疾病知识和抗病毒治疗的接受程度.%Objective To evaluate the affect of hepatitis C virus (HCV) education in chronic hepatitis C patients' disease related knowledge and antiviral treatment acceptance in rural china.Methods Rural HCV patients of attended CHC project of HCV education.Doctor delivered subsequent interactive lecture,and patients completed pre-and post-education questionnaires before and after taking the lectures.Results 151 CHC patients were included.Mean age was 57.3 years old,50.3％ were male,51.0％ of the students had primary school education or illiterate,and 76.2％ had a monthly income below RMB 3,000.98.0％ of patients defined their baseline HCV knowledge as "nothing" or "a little bit".A multivariate analysis reveled baseline knowledge scores were associated with age and household income.After education,mean knowledge score (range:0-28) increased from 13.1 to 23.0 (P ＜ 0.001) and average percent of patients with correct answers from the topic rose from 46.8％ to 82.1％ (P ＜ 0.001),and patients' antiviral treatment acceptance increased from 33.9％ to 65.6％ (P ＜ 0.001).Conclusion A rural Chinese patients had less education,HCV education delivered on the preferred format of patients substantially improved hepatitis C patients' disease-related knowledge and antiviral treatment acceptance in rural china.
展开▼
