目的 分析2006～2007年全国化妆品皮肤病不良反应的发生情况,为化妆品监测及开展健康教育干预活动提供数据支持.方法 以2006～2007年卫生部化妆品不良反应监测网络的13家监测点医院皮肤科门诊的患者为调查对象,临床诊断依据国家颁布的<化妆品皮肤病诊断标准及处理原则>,记录患者使用化妆品与皮肤疾病相关信息,汇总数据并进行统计分析.结果 2006～2007年共监测化妆品不良反应病例数3128例,其中男性为181例,女性为2947例;病例主要集中在21～45岁年龄段(占81.0%);化妆品接触性皮炎共2591例(占82.9%);化妆品不良反应病例共涉及化妆品5959种,以护肤类化妆品最多(占72.14%);对其中105例祛斑类化妆品发病时间及气象条件的研究表明,发生在6～9月份的病例最多,随温度和湿度升高其发病数量也相应升高.结论 化妆品不良反应主要见于21～45岁年龄段的女性,接触性皮炎发生率最高,护肤类化妆品引起的不良反应病例最多.因此应加强监测并积极开展针对使用人群的健康教育干预活动.%Objective To summarize the information of cosmetic adverse reaction in China between 2006 - 2007 and to provide data for supervision and health education. Methods 13 medical organizations were selected for monitoring skin diseases induced by cosmetics. The outpatients were conducted according to 《Diagnostic criteria and principles of management of skin diseases induced by cosmetics》. The general information of cases were collected and analyzed by SPSS. Results A total of 3128 cases of cosmetic adverse reaction were reported between 2006 - 2007. Among these cases, 2947 patients were female and 181 male. 81.0％ of patients were at age of 21 -45. 2591 (82.9％) cases were diagnosed as irritant contact dermatitis. About 5959 cases were observed with cosmetic adverse reaction. The cases induced by spot banishing cosmetics were usually observed from June to September, and more occurred in weather of high temperature and humidity. Conclusion The young and middle aged females were the most susceptible to cosmetic adverse reaction,and irritant contact dermatitis was most common. The supervision of cosmetics and health education should be strengthened.
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