老年综合评估在弥漫大B细胞淋巴瘤中应用的研究

摘要

老年弥漫大B细胞淋巴瘤(DLBCL)患者的发病率逐年增高,而老年患者异质性较大,如何恰当将这些患者分层,并给他们最适合的治疗是目前临床工作面临的重要问题.老年综合评估(CGA)从老年医学角度对患者进行全面评估,有助于判断预后,评价治疗耐受力,并有可能进一步指导治疗,使老年DLBCL患者得到精准治疗.现对国内外CGA在DLBCL中应用的研究进行综述,为制定恰当的DLBCL患者的CGA系统提供依据.%The incidence of elderly patients with diffuse large B cell lymphoma(DLBCL)are increasing year by year.Elderly patients have great heterogeneity.How to properly stratify these patients and give them the most suitable treatment is the challenge we are facing.Comprehensive geriatric assessment(CGA)conduct a comprehensive assessment of the patients from the perspective of gerontology,which is helpful to judge the prognosis,to evaluate the tolerance of treatment,to further guide the treatment,and to accurate treatment of elderly DLBCL.This article reviews the research on the application of CGA in DLBCL at home and abroad,so as to provide evidence for developing the appropriate comprehensive evaluation system for the elderly patients with DLBCL.