炎症性肠病发病机制的研究进展

摘要

The inflammatory bowel disease (IBD) , mainly consisting of Crohn' s disease (CD) and ulcerative colitis UC) , is characterized by persistent intestinal inflammation. Although the exact pathogenesis of IBD is unknown, it isenerally accepted that the uncontrolled immune response leads to intestinal inflammation with the effect of environmentalictor in genetically predisposed individuals.%炎症性肠病(inflammatory bowel disease,IBD)主要包括克罗恩病(crohn's disease,CD)和溃疡性结肠炎(ulcerative colitis,UC),是一组以持续性肠道炎症为特征的疾病.其确切的发病机制尚不十分明确,一般认为是环境因素作用于遗传易感的个体,使其免疫系统发生过度的免疫反应,最终导致肠道炎症.