高压氧治疗颅脑损伤的临床疗效探索

摘要

Objective To observe the clinical effect of hyperbaric therapy for craniocerebral trauma. Method 230 cases of patients with craniocerebral trauma after surgery as studied object, were randomly divided into experimental group and control group. Two groups were given same conventional therapy after surgery, experimental group were added with hyperbaric therapy. Statistical two groups of patients GOS score, MMSE score and complications were observed. Result ①GOS score of experimental group were signiifcantly higher than that in control group (P<0.01).②MMSE items such as orientation ability, memory ability, attention and computing ability, memory ability and language ability of experimental group were signiifcantly higher than that in control group (Pal <0.01). ③Complication rate of experimental group were signiifcantly higher than that in control group (P<0.05). Conclusion Hyperbaric therapy for craniocerebral can decrease the risk after surgery, enhance life quality after surgery, and the safety can be controlled basically, so it deserves considering in clinical work.%目的：观察高压氧治疗颅脑损伤的临床效果。方法选取本院230例颅脑损伤术后患者作为研究对象，随机分为观察组和对照组，每组各115例。对照组患者予以抗炎、神经恢复药物、营养支持等常规治疗，观察组患者在对照组治疗基础上采用GY2672/0.3-16IV型高压氧舱在患者身心状况基本稳定后予以高压氧治疗。统计两组患者格拉斯哥预后（GOS）评分、简易精神状态评价量表（MMSE）评分以及并发症发生情况。结果①观察组患者GOS评分显著高于对照组（P＜0.01）；②观察组患者MMSE量表中定向能力、记忆能力、注意和计算能力、回忆能力和语言能力均显著高于对照组（P均＜0.01）；③观察组患者并发症发生率显著低于对照组（P＜0.05）。结论高压氧治疗颅脑损伤患者，可有效降低患者术后风险，提高术后生活质量，安全性和可控性高，对于改善患者预后具有重要意义，值得临床应用并推广。