目的：评价急诊经皮冠状动脉介入治疗（PCI）高龄（≥80岁）急性冠状动脉综合征（ACS）患者的安全性与有效性。方法选择124例高龄ACS患者作为研究对象，按照患者治疗意愿分为观察组（PCI治疗组，73例）与对照组（保守治疗组，51例），比较两组患者超声心动图（ECHO）量化评价及术后随访情况。结果两组患者治疗前各项ECHO指标比较并无明显差异（P＞0.05），治疗后左室射血分数（LVEF）、左心室短轴缩短率（FS）、左心室舒张末期容积（LVVd）及收缩末期容量（LVVs）均较治疗前明显改善（P＜0.05），治疗组较对照组改善明显（P＜0.05）；观察组患者不良心脑血管事件（MACCEs）发生率明显低于对照组，差异具有显著性（P＜0.05）。结论 PCI可明显改善高龄（≥80岁）ACS患者心功能状态，具有良好的有效性和安全性，但应注意随访期间出血情况的发生。%Objective To evaluate the safety and validity of emergency percutaneous coronary intervention for elderly patients (≥80 years old) with ACS. Method 124 cases of elderly patients with ACS were selected as the research object, according to patients' aspiration, they were divided into observation group (PCI treatment group) for 73 cases and control group (conservative treatment group) for 51 cases;the quantitative evaluation, success rate, complications and postoperative follow-up condition of ECHO for two groups were analyzed. Result Before treatment the ECHO index comparison of the two groups of patients had no significant difference (P > 0.05), after treatment, LVEF, FS, LVVd and LVVs levels were signiifcantly improved (P<0.05), but the contemporary comparison of the treatment group in treatment group improved signiifcantly than that control group at same period (P<0.05);incidence rate of MACCEs of observation group was signiifcantly lower than that of control group (P<0.05). Conclusion Treating elderly patients (≥80 years old) ACS patients by PCI can evidently improve cardiac function, it has a good effectivity and safety, but the happeness for bleeding should be paid attention to during the follow-up period.
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