0.1他克莫司软膏治疗老年慢性唇炎的临床观察

摘要

Objective Discuss the curative effects of 0.1% Tacrolimus ointment to gerontism chronic cheilitis. Methods Choose 60 patients of gerontism chonic cheilitis, divided them into 2 groups randomly, 30 patients each. For observation group, apply 0.1%Tacrolimus ointment externally once each in the morning and evening a day, totally for 10 days. For control group, apply triamcinolone acetonide and econazole nitrate cream externally once each in the morning and evening a day, totally for 10 days. Make observation at 5&10 days before and after treatment. Results It is much better of the curative effects in observation group than in control group, and the untoward effects are less in observation group too. Conclusion It is better and safer for 0.1%Tacrolimus ointment to cure gerontism chronic cheilitis.%目的：探讨0.1%他克莫司软膏治疗老年慢性唇炎的疗效。方法入选60例老年慢性唇炎患者，随机分为两组，各30例。试验组：外涂0.1%他克莫司软膏，早晚各1次，共10天；对照组：外涂曲安奈德益康唑乳膏，早晚各1次，共10天；于治疗前及治疗后5天、10天观察临床疗效。结果试验组疗效明显优于对照组，不良反应少。结论0.1%他克莫司软膏治疗老年慢性唇炎疗效确切，安全性高。