Objective To comparison of contractility of uterus smooth muscle in puerperant with single pregnancy and twin pregnancy. Method 64 pregnant women who underwent cesarean section from August 2014 to August 2015 in Urumqi Friendship Hospital were selected as the subjects. Among them, 32 cases of single pregnant women and 32 cases of twins pregnant women. They were examined by using all the samples of maternal uterine muscle. The muscle strips were fixed in Maxwell's tubules by in vitro culture, and the oxytocin was stimulated by different concentrations of oxytocin. The contractility of uterus smooth muscle was compared with single and twin pregnancy women. Result Under the influence of low concentration oxytocin and high concentration oxytocin, the contractility of uterus smooth muscle of single pregnant women were greater than that twin pregnant women (P<0.05). Under the influence of high concentration oxytocin, the contractility of uterus smooth muscle in single and twin pregnant women were greater than that of low concentration oxytocin (P<0.05). When the concentration of oxytocin was 1~10 mol/L, the contractility of uterus smooth muscle changed the most, and the contractility of uterine smooth muscle reached the maximum when the concentration of oxytocin was 10 mol/L. Conclusion In different environments, the contraction of uterine smooth muscle of twin pregnant women are lower than that of single pregnant women, so it is very important to timely check and prevent the occurrence of adverse events in pregnant women with low contractility.%目的 分析单胎妊娠和双胎妊娠产妇的子宫平滑肌收缩力.方法 选取乌鲁木齐市友谊医院2014年8月2015年8月行剖宫产的产妇64例为研究对象,其中单胎妊娠产妇与双胎妊娠产妇各32例,取所有产妇子宫肌样本进行检验.采用离体培养的方法将肌条纵向固定于麦氏浴管中,给予肌条不同浓度的缩宫素刺激,通过换能器记录并比较单胎妊娠与双胎妊娠产妇子宫平滑肌的收缩力.结果 在低浓度缩宫素和高浓度缩宫素作用下,单胎妊娠产妇子宫平滑肌收缩力均大于双胎妊娠产妇(P<0.05).在高浓度缩宫素作用下,单胎和双胎妊娠产妇子宫平滑肌收缩力均大于低浓度缩宫素作用下子宫平滑肌收缩力(P<0.05);在缩宫素浓度为1~10 mol/L时,子宫平滑肌收缩力变化最显著,且当缩宫素浓度为10 mol/L时子宫平滑肌收缩力达到最大值.结论在不同环境下,双胎妊娠产妇子宫平滑肌收缩力均低于单胎妊娠产妇.因此,子宫平滑肌收缩力较低的双胎妊娠产妇及时进行定期检查,对预防不良事件的发生具有重要意义.
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