一起新型甲型H1N1流感疫情的临床和实验室特点

摘要

目的 分析一起新型甲型H1N1流感疫情患者的临床和实验室特点.方法 某部集体发病患者35例,均由核酸检测方法确诊;回顾调查患者的密切接触史、实验室检测结果、治疗和预后等.结果 本次疫情收治的35人,密切接触平均1.7 d出现临床症状,首发症状为发热占97.1%(34/35),咽痛65.7%(23/35),咳嗽51.4%(16/35),肌肉酸痛31.4%(11/35),头痛28.6%(10/35).病毒核酸检测阴性的平均天数为4.5 d,奥司他韦治疗,5 d标准疗程,所有患者7 d后痊愈出院.结论 本次疫情为比较典型的新型甲型H1N1流感.%Objective To analysis the clinical and laboratory characteristics of Patients infected with new influenza A (H1N1) virus.Methods All cases with new influenza A (H1N1) confirmed on polymerase chain reaction assay on throat swabs.There were included in a prospective evaluation of clinical characteristics,laboratory results,treatment and overcome of new influenza A (H1N1).Results There were 35 patients in the epidemic.Clinical illness developed within a mean of 1.7 days.Fever occurred in 97.1%,sore throat 65.7% cough 51.4%,headache 28.6%,and myalgia 31.4%.All patients were treated with oseltamivir lasted 5 days.The mean duration of viral shedding was 4.5 days.All were cured and left hospital after day 7.Conclusion It was infected by new influenza A (H1N1) typically in this epidemic.