急性肺栓塞患者生活质量及其影响因素调查

摘要

目的 探讨急性肺栓塞患者生活质量(QOL)及其影响因素.方法 60例急性肺栓塞患者完成贝克抑郁量表、状态-特质焦虑量表及SF-36生活质量调查问卷;SF-36 调查问卷包括躯体评分(PCS)及精神评分(MCS)两部分.60例年龄、性别匹配的社区慢病患者作为对照组.以生活质量PCS及MCS作为因变量,肺栓塞生活质量影响因素作为自变量,进行多元线性回归法分析,评估肺栓塞患者QOL相关影响因素.结果 与社区对照患者比较,急性肺栓塞患者生活质量显著下降(P＜0.05),抑郁水平(P＜0.05)和焦虑水平(P＜0.01)均明显升高,且PCS及MCS评分均与动脉血氧分压(PaO2)呈正相关(P＜0.01),与抑郁评分呈负相关(P＜0.05);PCS评分还与下肢深静脉血栓形成(DVT)史呈负相关(P＜0.05).结论 急性肺栓塞患者生活质量明显下降.PaO2、抑郁评分、DVT史是影响患者生活质量的重要因素.%Objective To discuss the quality of life ( QOL ) and influence factors in patients with acute pulmonary embolism ( APE ). Methods The patients with APE ( APE group,re = 60 ) filled in the Beck Depression Inventory ( BDI ), State-Trait Anxiety Inventory ( STAI ), and the SF-36 questionnaire. The SF-36 questionnaire consisted of physical component summary ( PCS ) and mental component summary ( MCS ). Other 60 patients with chronic diseases matched by age and sex in the community were enrolled in control group. A multiple linear regression analysis was conduced taking PCS and MCS of QOL as dependent variable and influence factors on QOL as independent variable. Results Compared with control group, QOL decreased significantly ( P < 0. 05 ), and the levels of depression ( P < 0. 05 ) and anxiety ( P <0.01 ) increased significantly in APE group. The scores of PCS and MCS were positively related to artery blood oxygen pressure ( PaO2 ,P <0. 01 ) and negatively related to depression score ( P <0.05 ). The score of PCS was negatively related to the history of deep vein thrombosis ( P <0. 05 ). Conclusion QOL decreases significantly in APE patients, and PaO2 , depression score and history of deep vein thrombosis are important factors influencing QOL.