Objective To explore the quality of life and related factors among people living with HIV/AIDS in Guangdong province.Methods A total of 443 subjects older than age 18 who had been diagnosed as HIV/AIDS were recruited from AIDS Outpatient Clinic Departments in Guangzhou and Shenzhen.HIV/AIDS-targeted quality of life (HAT-QoL) scale was used to measure the quality of life on the patients.Nonparametric test method and multiple linear regression analysis were performed to explore the related factors.Results The average scores of the following nine domains of HIV/AIDS-targeted quality of life scales were:overall function as 59.89 ± 23.35,concerns on medication as 62.91 ± 24.01,worries on factors as being disclosed,on health,on financial situation were 19.97 ±23.04,54.05 ± 12.24 and 35.94 ± 26.45,respectively,trust on providers as 68.72 ± 26.17,rate of understanding HIV as 61.46 ± 25.72,on life satisfaction as 56.90 ± 25.30 and on sexual function as 50.82 ± 23.86.Factors associated with quality of life would include sex,age,residencial area,education,employment,marital status,complications,HAART-related prescriptions,route of infection and duration of HIV/AIDS etc.Conclusion The quality of life among HIV/AIDS patients had declined,especially on worries related to disclosure and financial situation.More attention should be paid on those with poor education,low income and lack of family support in order to improve their quality of life and reducing mortality.%目的 了解广东省HIV感染者/艾滋病患者(HIV/AIDS)生活质量,并探讨其影响因素.方法 采用HIV/AIDS生活质量量表(HAT-QoL),对在广州市第八人民医院和深圳市第三人民医院就诊的443例年龄≥18岁HIV/AIDS进行生活质量评价,采用非参数检验方法对生活质量各维度的影响因素进行单因素分析,采用多元线性逐步回归方法进行多因素分析.结果 HIV/AIDS生活质量的总体功能、用药感受、暴露担忧、健康担忧、医生信任度、经济担忧、HIV掌握率、生活满意度和性生活9个维度的平均得分分别为59.89±23.35、62.91±24.01、19.97±23.04、54.05±12.24、68.72±26.17、35.94±26.45、61.46±25.72、56.90±25.30和50.82±23.86.单因素和多元线性回归分析结果表明,性别、年龄、户籍类型、教育程度、工作状态、有无伴偶、是否有并发症、是否抗病毒治疗、感染方式、感染时间等因素,与HIV/AIDS的生活质量各个维度有关.结论 广东省HIV/AIDS生活质量偏低,尤以暴露担忧和经济担忧为甚,社会人口学和HIV感染状况等因素在不同方面影响HIV感染者的生活质量,应加强低文化程度、低收入和缺少家庭支持人群的医疗和社会支持.
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