首页> 中文期刊> 《中国药物应用与监测 》 >吉西他滨相关性贫血的主动监测研究

吉西他滨相关性贫血的主动监测研究

             

摘要

目的:利用住院患者药品不良事件主动监测与评估警示系统分析吉西他滨致贫血的发生规律。方法:回顾性调取我院2013年1-3月期间的住院患者病例,设置吉西他滨相关性贫血主动监测的事件配置器参数,分析系统的阳性报警率以及不良反应发生率,并对吉西他滨致贫血的相关因素进行分析。结果:系统阳性报警率为94.74%,吉西他滨相关性贫血的发生率为25.53%;本研究未发现性别、年龄对吉西他滨致贫血的影响差异。结论:住院患者药品不良事件主动监测与评估警示系统可以实现化疗相关性贫血的主动监测,且系统报警准确率高,可以达到早期预防的目的,同时可降低临床用药风险,具有良好的应用前景。%Objective: To analyze the regularity of anemia caused by gemcitabine with inpatient's active monitor and assessment system of adverse drug events. Methods:Hospitalized patients in our hospital from January to March in 2013 were extracted, event configuration parameters for monitoring anemia caused by gemcitabine were set, and positive warning rate, incidence rate of adverse reactions and related factors associated with anemia caused by gemcitabine were analyzed. Results:Positive warning rate was 94.74%, incidence rate of anemia caused by gemcitabine was 25.53%. There was no signiifcant difference in incidence of anemia caused by gemcitabine between gender and age in this study. Conclusion: The active surveillance of anemia caused by chemotherapy can be realized by inpatient's active monitor and assessment system of adverse drug events with high accuracy, which can realize early prevention and reduce the risk of clinical medication, it has a good application prospect.

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