Objective To observe the effect of Gengjian decoction and hyperbaric oxygen therapy on peri-menopausal women with sleep disorders. Methods 60 peri-menopausal women with sleep disorders were divided into treatment group ( n = 30 ) and the traditional Chinese medicine group( n = 30 ). Patients in the traditional Chinese medicine group were administrated with Gengjian decoction, treatment group were administrated with Gengjian decoction together with hyperbaric oxygen therapy, following up 3 months. Effective rate, onset time, and the changes of Pittsburgh sleep quality index ( PSQI ) in two groups were observed. Results The effective rate ( 93. 3% ) was higher and the onset time ( 6. 2 d ±2. 1 d) was shorter in treatment group than those in traditional Chinese medicine group ( 70. 0% , 7. 6 d ± 1. 9 d, P <0. 05 ). The PSQI score, sleeping time, sleeping efficiency, dyssomnia improvement were better in treatment group than traditional Chinese medicine group( P <0. 05 ). Conclusion The Gengjian decoction combined with hyperbaric oxygen therapy could effectively improve sleep quality of peri-menopausal women.%目的 观察自拟更健汤联合高压氧治疗妇女围绝经期睡眠障碍的临床效果.方法 将60例围绝经期睡眠障碍患者分为治疗组和中药组各30例.中药组给予自拟更健汤;治疗组给予自拟更健汤联合高压氧治疗;随访3个月.观察2组有效率、起效时间及匹兹堡睡眠质量指数(PSQI)的变化.结果 治疗组总有效率(93.3%)明显高于中药组(70.0%),差异有统计学意义(P<0.05).治疗组起效时间短于中药组(6.2 d±2.1 d vs 7.6 d±1.9 d),差异有统计学意义(P<0.05).治疗组睡眠质量、睡眠时间、睡眠效率、睡眠障碍及PSQI得分均较中药组显著,差异有统计学意义(P<0.05).结论 自拟更健汤联合高压氧治疗能有效地提高围绝经期患者的睡眠质量.
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