Objective To invesligale the hypertonic solution improves early recovery of traumalic shock effect of oxygen supply and demand imbalance. Methods 60 palienls with traumalic shock were randomly divided into 2 groups, all 30 cases. A group: Select fluid resuscitation iherapy, combined with hypertonic resuscitation fluid for Ho Su; B group: choice of tradilional fluid resuscitation iherapy, such as exudale compound with sodium chloride injection to recovery. Observed and recorded 2 groups before treatment and after 2 hours SvO2 (venous oxygen saturation) , HCT (hematocrit) , Lac (lactate) , BD (base deficit) , the treatment end point mortality and MODS ( multiple organ dysfunction syndrome) incidence, and comparative analysis. Results Before treatment SvO2, Lac, HCT, BD and other indicators showed no significant difference between (P>0.05). 2 hours after treatment, compared with B, A marked increase in group SvO2; Lac, BD decreased significantly; two groups has declined HCT, but especially B group; a highly significant difference (P<0. 01). Disease mortality end point; A group 3. 33% , B group 13. 33% ; MODS rale; A group 20% , B group 60% ; difference was statistically significant ( P < 0. 05 ) . Conclusion Compared wilh olher exudate, hypertonic solution improves efficiency of traumalic shock resuscitation, and can significantly improve the oxygen supply and demand imbalance, can be used as an early choice for traumalic shock resuscitation.%目的 探讨高渗复合液对创伤性休克患者复苏早期氧供需失衡的影响.方法 将60例创伤性休克患者随机分成两组,各30例.A组:选择限制性液体复苏疗法,采用高渗复合液(贺苏)进行复苏;B组:选择传统液体复苏疗法,采用等渗液"复方氯化钠注射液"进行复苏.观察记录两组用药前及用药2 h后静脉血氧饱和度(SvO2)、血细胞比容(HCT)、血乳酸(Lac)、碱缺失(BD),治疗终点死亡率和多器官功能障碍综合征(MODS)发生率,并进行比较分析.结果 两组在治疗前SvO2、Lac、HCT及BD等指标间比较差异无统计学意义(P>0.05).治疗2 h后,与B组比较,A组SvO2明显上升,Lac、BD明显下降;两组HCT均有所下降,但B组尤为明显,差异有统计学意义(P＜0.01).病程终点死亡率:A组3.33%,B组13.33%;MODS发生率:A组20%,B组60%;两组比较差异均有统计学意义(P＜0.05).结论 与等渗液比较,高渗复合液对创伤性休克复苏效率高,而且能明显改善氧供需失衡,可作为创伤性休克复苏早期首选.
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