AIM: To investigate the effects of adhesive systems, lining materials and the resin matrices onrnthe marginal microleakage of composite resin restorations. METHODS: Class II cavities were prepared on 100 freshly extracted molars. The molars were then randomly divided into 5 groups (re =20) and the cavities were filled with 3M Adper Easy One + 3M Z250 (Group A) , 370g/L phosphoric acid + 3M Adper Single Bond 2 + 3M Z250 (Group B) , 3M Adper Easy One +3M Light Cure Glass Ionomer + 3M Z250 (Group C) , 3M Adper Easy One + 3M Flow-able Restorative + 3M Z250 (Group D) and 3M P90 system adhesive + 3M P90 (Group E). After thermocycling and Indian ink dyeing, all specimens were sectioned in mesio-distal direction. The dye penetration depth was observed and measured under stereomicroscope. RESULTS: The mean microleakage of group E was significantly less than that of the other groups ( P < 0. 05 ). The mean microleakage of group C was significantly less than that of group A, B, and D (P<0.05). No significant difference was observed among groups A, B and D (P>0 05). CONCLUSION: The microleakage of P90 restoration is low. Lining by light-cured glass ionomer can decrease the microleakage of composite resin. Total-etch adhesive and self-etch adhesives have no significantly different effects on the microleakage of composite resin.%目的:观察不同粘结系统、不同垫底材料,不同树脂基质对复合树脂边缘微渗漏的影响.方法:按标准在100个新鲜离体磨牙制备邻(牙合)面洞后,随机分为5组(n=20),分别用3M自酸蚀粘结剂+3MZ250复合树脂充填(A组)；370 g/L磷酸酸蚀剂+3M全酸蚀粘结剂+3M Z250复合树脂充填(B组)；3M自酸蚀粘结剂+3M光固化玻璃离子垫底+3M Z250复合树脂充填(C组)；3M自酸蚀粘结剂+3M流动树脂垫底+3M Z250复合树脂充填(D组)；3M P90粘结系统+3M P90复合树脂充填(E组).所有试件经过冷热循环、印度墨水染色,近远中向切片后,在体视显微镜下观察测量染料渗透深度.结果:E组(P90)的微渗漏均数明显小于其余各组(P＜0.05)；C组的微渗漏均数明显小于A组、B组和D组(P＜0.05);A、B、D3组间两两相比差异均无统计学意义(P＞0.05).结论:P90复合树脂充填组的微渗漏最小；光固化玻璃离子垫底可以改善复合树脂微渗漏；全酸蚀粘结剂和自酸蚀粘结剂对复合树脂微渗漏的影响无显著性差异.
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