一种用于局部红外线照射的大鼠简易固定装置

摘要

目的 通过简易材料制作一种用于局部红外线照射的大鼠固定装置,并观察在该装置固定下大鼠保定效果.方法 SD大鼠12只,应用固定装置固定大鼠,分别观察在室温(24~26℃)、38~39℃及42~43℃红外线局部照射下的保定时间,最大以60 min为观察终点.结果 大部分大鼠(10/12)在室温(24~26℃)、38~39℃及42~43℃红外线局部照射下保定时间都能达到30 min以上,其中有8只可达到60 min,不同局部温度下大鼠的保定时间差异无显著性(P > 0.05).结论 该装置制作简单,操作简便,能实现较长时间的保定,是一种较为方便、可靠的大鼠保定装置.%Objective To construct a rat fixation device for local infra-red irradiation in rats, observe the binding effect of this fixation device, and assess its practical application.Methods Twelve SD rats were held by this home-made simple device.The holding time was recorded at room temperature (24℃ to 26℃), 38℃ to 39℃ and 42℃ to 43℃ by infrared irradiation, respectively, and the maximum observation point was 60 min.Results Most rats (10/12) were held for more than 30 minutes at room temperature, 38℃ to 39℃ and 42℃ to 43℃ infrared irradiation.While 8 rats reached 60 min.There was no statistically significant difference among the holding times at various temperatures (P > 0.05).Conclusion This self-made device is simple, easy to operate and can be used to hold rats for a long time, and is a convenient and reliable holding device in animal experiments.