近红外线血氧检测技术对乳腺疾病的诊断价值

摘要

目的:探讨近红外线血氧检测技术对乳腺良恶性疾病的诊断价值.方法:用乳腺血氧检测仪对101例乳腺病变进行血氧检测,并对其进行病理检查及微血管密度(MVD)的测定.结果:乳腺良恶性病变组织的血含量值分别为0.0634±0.2290和-0.1464±0.2417,恶性病变组织的血含量明显高于良性病变(P<0.001);良、恶性病变组织的氧含量值分别为1.1888±0.3117和0.9969±0.4779,恶性病变组织的氧含量明显低于良性病变(P=0.019).血氧含量值与MVD值之间无相关性.乳腺良性病变与浸润性导管癌的MVD值差异有统计学意义(P=0.037).结论:乳腺癌组织具有"高血低氧"特征.用近红外线乳腺血氧检测技术判断乳腺病变的良恶性是可行的,该技术对乳腺癌有较高的诊断价值.%Objective:To evaluate the diagnostic value of near-infrared detection technique in patients with benign or malignant breast diseases by detecting blood concentration and blood oxygen concentration. Methods: The hemoglobin concentration and blood oxygen saturation of 101 breast lesions were detected by the near-infrared breast detecting instrument. The pathologic slides and the microvessci density (MVD) of those lesions were also observed. Results: The hemoglobin saturation of the breast benign and malignant lesions were 0. 0634 + 0. 2290 and -0. 1464 + 0. 2417, respectively, significantly higher in the malignant lesions than in the benign oncsCP^O. 001). The blood oxygen saturation of the breast benign and malignant lesions were 1. 1888 + 0. 3117 and 0. 9969 + 0. 4779, respectively, significantly lower in the malignant lesions than in the benign oncs(P = 0. 019). There was no linear correlation between MVD and hemoglobin concentration or blood oxygen saturation. The MVD of invasive ductal carcinoma was significantly higher (P - 0. 037) than that of the benign breast lesions. Conclusions: Breast cancer is characterized by higher hemoglobin concentration and lower blood oxygen saturation. It is feasible to use near-infrared breast detecting technique to discriminate breast malignant lesions from benign ones by detecting breast hemoglobin concentration and blood oxygen saturation.