不同病理类型非霍奇金淋巴瘤18 F-氟代脱氧葡萄糖 PET／CT 标准摄取值的比较

摘要

目的：探讨18 F‐氟代脱氧葡萄糖（fluorine‐18 flurodeoxyglucose ，18 F‐FDG）PET／CT 的标准摄取值（standardized uptake value ，SUV）对不同病理类型非霍奇金淋巴瘤（non‐Hodgkin lymphoma ，NHL）的鉴别诊断价值。方法：回顾分析246例初发NHL患者的18 F‐FDG PET／CT显像资料，比较侵袭性与惰性 NHL、B细胞与 T／NK细胞 NHL间的SUV差异。结果：194例侵袭性NHL的SUV为18．5±9．6，35例惰性NHL的SUV为8．7±6．2，差异有统计学意义（P＜0．01）。214例B细胞NHL的总 SUV 为20．0±9．7，32例 T／NK 细胞 NHL 的总SUV 为11．6±5．2，差异有统计学意义（P＜0．01）。结论：18 F‐FDG PET／CT检查中，SUV对NHL的病理分型有一定的参考价值。%Objective:To explore the role of the standardized uptake value(SUV) of Fluorine‐18 flurodeoxyglucose(18 F‐FDG) PET/CT in differentiating the types of non‐Hodgkin lymphoma(NHL) .Methods:The 18 F‐FDG PET/CT data of 246 patients with initial onset NHL were retrospectively analyzed .The SUVs between aggressive and indolent NHL ,as well as that between B and T/NK cell NHL ,were compared .Results:The SUV in 194 cases of aggressive NHL was 18 .5 ± 9 .6 ,while that in 35 cases of indolent NHL was 8 .7 ± 6 .2 ,and there was significant difference between them(P<0 .01) .The SUV in 214 cases of B cell NHL was 20 .0 ± 9 .7 ,while that in 32 cases of T/NK cell NHL was 11 .6 ± 5 .2 ,and there was significant difference between them(P<0 .01) .Conclusions:During the 18 F‐FDG PET/CT examination ,SUV has some reference value for differentiating pathological types of NHL .