Ion chromatography (IC) has been a well-established technique for the analysis of ionic samples. The aqueous solution used for IC eluent is well suited for bioanalysis in relative to common liquid chromatography. This is especially true for capillary ion chromatography (CIC) due to its advantage of small sample needed. CIC is generally divided into three categories including open tubular, packed and monolithic. In this review, the recent progress of CIC is summarized based on the development of several key components associated with packed column-based system. The development of open tubular ion chromatography is also reviewed.%离子色谱是目前分析离子型样品的成熟技术,其水相工作介质的特点相对于液相色谱更适合于生物样品的分析.毛细管离子色谱(CIC)由于其节省样品的特点在生物分析方面的优势更为明显.CIC大体上可分为开管型、填充柱型和整体柱型3种类型.本文以填充型CIC几大关键部件技术发展为主线,综述了近年来CIC的研究进展.
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