Synthesis of Novel gem-Difluoromethylene-containing 1,2,3-Triazoles via Click Reaction

摘要

Seventeen novel gem-difluoromethylene-containing 1,2,3-triazoles were synthesized by the click reaction of ethyl 2-azido-2,2-difluoroacetate and terminal alkynes in the presence of 10 mol% CuI.