Objective: To study effect of bicycling on prognosis of aged patients with stable angina pectoris (SAP). Methods; A total of 82 aged SAP patients were randomly divided into exercise group (n = 40, received bicycling and routine medical treatment for four months) and routine treatment group (n=42, received routine medical treatment). Plasma levels of C-reactive protein (CRP), interleukin-6 (IL-6), thromboxan A2 (TXA2) and low density lipo-protein-cholesterol ( LDL-C) were measured and compared before and after study. Incidence rates of major adverse cardiovascular events (MACE) of the two groups were followed up. Results: Compared with before treatment, levels of CRP, IL-6, TXA2 and LDL-C of the two groups significantly decreased after treatment (P<0. 05 all), and there were no significant difference between the two groups. Both groups were followed up for two years, incidence rate of MACE in exercise group was significantly lower than that of routine treatment group (15. 8% vs. 44. 7% , P<0. 01). Conclusion; Bicycling could significantly improve prognosis of aged patients with stable angina pectoris.%目的:探讨踏车运动对老年稳定型心绞痛患者预后的影响.方法:82例老年稳定型心绞痛患者被随机分成踏车运动组(40例):进行踏车运动和常规药物治疗4个月,常规治疗组(42例):行常规药物治疗.测定试验前后血浆C-反应蛋白(CRP)、白介素-6(IL-6)、血栓素A2 (TXA2)、低密度脂蛋白-胆固醇(LDL-C)水平,并随访两组间主要不良心脏事件(MACE)的发生率.结果:两组治疗后较治疗前血浆CRP、IL-6、TXA2、LDL-C水平均有明显下降(P＜0.05),且两组间比较无显著差异；两组治疗后均随访2年,踏车运动组MACE的发生率较常规治疗组明显减少(15.8％比44.7％,P＜0.01).结论:踏车运动对老年稳定型心绞痛患者预后有明显改善作用.
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