Objective: To analyze echocardiographic and electrocardiographic features of patients with cardiac amy-loidosis (CA). Methods: Combined with clinical and pathological examinations, a total of 20 CA patients were diagnosed in our hospital from Jul 2003 to Oct 2011, and their echocardiographic and electrocardiographic features were retrospectively analyzed. Results: All 20 patients showed interventricular septal thickening [ (15. 67 ± 3. 60) mm] and left ventricular posterior wall concentric thickening [ (15. 73 ± 3. 54) mm], but their left ventricular volume were normal; diastolic dysfunction existed in all patients; 19 cases (95%) possessed left atrial enlargement, 17 cases (85%) showed particle-like reflect light enhancement in subendocardial myocardium, 11 cases (55%) occurred moderate-large hydropericardium by echocardiography. The voltage of all limb leads of electrocardiogram were low in all 20 patients, incidence rates of limb lead low voltage and pseudo-infarction Q waves were 55% and 45% respectively. Conclusion: For patients with unknown heart failure, if echocardiography shows ventricular hypertrophy, normal ventricular volume, particle-like reflect light enhancement in subendocardial myocardium and possess limb lead low voltage or pseudo-infarction Q waves of electrocardiogram, then cardiac amyloidosis should be considered, and patients should further receive pathological biopsy examination etc. in order to early diagnose and treat.%目的:分析心脏淀粉样变患者的心脏超声及心电图特点,为临床医师早期识别和诊断心脏淀粉样变性提供帮助.方法:2003年7月～2011年10月我院结合临床及病理检查确诊心脏淀粉样变性患者20例,回顾性分析其超声心动图和心电图特点.结果:心脏超声检查所见:20例患者均表现室间隔[(15.67±3.60) mm]及左心室后壁向心性增厚[(15.73±3.54) mm]而左心室容积正常；所有患者均存在舒张功能不全；多数患者有左心房增大(19例,95％),心内膜下心肌有颗粒样反光增强(17例,85％),出现中大量心包积液(11例,55％).心电图表现为:20例患者心电图肢体导联的电压均较低,肢体导联低电压和假性梗死Q波的发生率分别为55％和45％.结论:不明原因心力衰竭的患者,如果心脏超声示心室肌肥厚且心室容积正常,伴心内膜下心肌内有颗粒样反光增强,而心电图又表现为肢体导联低电压或非梗死性Q波时,应考虑心脏淀粉样变性的可能性.应进一步行病理活检等检查,以利于早期诊断和治疗.
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