生物酶法合成L-精氨酸衍生物的研究进展

摘要

L-arginine (L-Arg) is an alkaline amino acid that possesses various function groups and acts as an important precursor for useful chemical synthesis.L-Arg derivatives are widely applied in pharmaceutical,food and cosmetic industries.Environment friendly and cost-effective production of L-Arg derivatives by enzymatic catalysis provides significant advantages over chemical synthesis and microbial fermentation.In this article,several typical L-Arg derivatives and their enzymatic production processes are highlighted.Furthermore,prospect is also addressed about enzymatic production of L-Arg derivatives.%L-精氨酸是一种碱性氨基酸,具有多样化的官能团,是合成多种有用化合物的前体,其衍生物广泛应用于医疗、食品和化妆品等领域.L-精氨酸衍生物的合成方法有化学法、发酵法和酶法.在当前绿色经济和可持续发展的背景下,对比各种生产方法,生物酶法合成L-精氨酸衍生物具有明显优势.因此本文重点介绍了L-精氨酸衍生化的典型产品和合成技术,并介绍了生物酶法合成L-精氨酸衍生物未来可能的发展方向.