The recent development in carbon catabolite repression( CCR) and its effect on carbon resource utilization are summarized.Meanwhile, the co-utilization of the mixed carbon sources in engineered Escherichia coli are analyzed and prospected.%总结了大肠杆菌中C源分解代谢( carbon catabolite repression,CCR)现象的原理及特点,综述并分析了如何通过对宿主菌进行基因工程改造以解除碳代谢抑制,以实现大肠杆菌利用多种C源。
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