蛋白质序列的聚类结构分析

摘要

In this paper, the clustering structural analysis on protein sequences is given based on the granular space of a fuzzy proximity relation. Firstly, by using the MEGA software and introducing the inner product, the alignment distances of xylanse sequences are transformed into a fuzzy proximity relation ( or matrix). Secondly, its granular space is obtained by applying an algorithm. Finally, the clustering structural analysis on protein sequences and the method for determining optimal number of clusters are given. These researches provide a quantitative tool for analyzing protein sequences.%基于模糊邻近关系的粒度空间,对蛋白质序列进行聚类结构分析.利用MEGA软件计算选取的木聚糖酶序列间的比对距离,引入内积将其转化为模糊邻近关系(或矩阵),再应用算法求解其粒度空间,进行序列的聚类结构分析和最佳聚类确定研究.这些研究为蛋白质序列提供了定量分析的工具.