温胆汤辅助治疗对痰湿性不孕不育患者血清免疫抗体及疗效研究

摘要

目的：探讨温胆汤辅助治疗对痰湿性不孕不育患者血清免疫抗体及疗效的影响。方法收集痰湿性不孕不育患者52例，随机分为对照组和实验组，每组各26例，对照组患者给予枸橼酸氯米芬胶囊治疗，实验组在对照组基础上给予温胆汤治疗，治疗结束后，对所有患者的血清抗精子蛋白17抗体（anti-sperm protein 17 antibodies， Sp17Ab）、抗顶体蛋白酶抗体（anti-acrosin antibodies， AcrAb）水平及治疗效果进行检测。结果治疗后，与对照组比较，实验组患者的血清Sp17Ab水平较低（P＜0.05）；实验组患者的血清AcrAb水平较低（P＜0.05）；实验组患者的妊娠率较高（P＜0.05）。结论温胆汤辅助治疗能够显著降低痰湿性不孕不育患者血清Sp17Ab及AcrAb水平，提高妊娠率，改善治疗效果。%Objective To analyse effect of Wendan Tang adjuvant therapy on serum immune antibodies and efficacy in patients with phlegm dampness infertility.Methods 52 patients who were diagnosed with phlegm dampness infertility were collected.All patients were randomly divided into experimental group and control group, 26 cases in each group.Patients in control group received treatment with clomifene citrate capsules, patients in experimental group were given Wendan Tang treatment on the basis of control group treatment, after the treatment, the serum levels of Sp17Ab, AcrAb and treatment effect were detected in all patients.Results After treatment, compared with control group, the serum level of Sp17Ab was lower in experimental group(P<0.05); the serum level of AcrAb was lower in experimental group(P<0.05); the pregnancy rate was higher in experimental group(P<0.05).Conclusion The Wendan Tang adjuvant therapy can significantly reduce the serum levels of Sp17Ab and AcrAb in patients with phlegm dampness infertility,improve the pregnancy rate, improve the treatment effect.