Objective To study the efficacy and safety of amiodarone combined with Wenxin Granule in the treatment of unstable angina pectoris complicated with ventricular arrhythmia. Methods 80 cases of unstable angina pectoris and ventricular arrhythmia in our hospital were selected, were randomly divided into early death and experimental group, 40 patients in each group. The two groups were treated with antiplatelet therapy, anticoagulant therapy and other symptomatic treatment. The control group was treated with amiodarone, and the experimental group was treated with amiodarone and Wenxin granule. The safety and clinical efficacy of two groups of angina attack times were compared and analyzed. Results The experimental group had ventricular fibrillation and ventricular premature beat probability were 2.50% and 5.00% lower than the control group, the control group had adverse reaction of nausea and vomiting was 11 cases significantly more than the control group, with statistical difference (P<0.05). The experimental group 24 h in myocardial ischemia times (11.34±3.45) times the number was significantly less than the control group (20.80±4.87), the control group during the course of angina frequency (24.50±5.67) was significantly higher than the experimental group, there was significant difference (P<0.05). Conclusion The combination of amiodarone and Wenxin granule is effective and safe in the treatment of unstable angina pectoris complicated with ventricular arrhythmia.%目的 分析胺碘酮联合稳心颗粒治疗不稳定型心绞痛并室性心律失常有效性、安全性分析.方法 选取本院收治的80例不稳定型心绞痛并室性心律失常患者,随机分为对早卒和实验组,每组40例.2组患者均进行包括抗血小板治疗、抗凝治疗等对症治疗.对照组给予胺碘酮治疗,实验组进行胺碘酮、稳心颗粒联用治疗.比较分析2组心绞痛发作次数等安全性与临床疗效指标.结果 实验组发生室颤及室性早搏概率分别为2.50%与5.00%显著低于对照组,对照组发生恶心呕吐不良反应例数为11例,显著高于对照组,差异具有统计学意义(P<0.05).实验组24 h内心肌缺血次数为(11.34±3.45)次,显著少于对照组次数(20.80±4.87)次,对照组疗程期间发生心绞痛次数为(24.50±5.67)显著多于实验组,差异均具有统计学意义(P<0.05).结论 胺碘酮联用稳心颗粒对不稳定型心绞痛并室性心律失常患者的治疗效果较为理想,安全性高.
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