首页> 中文期刊> 《中国生化药物杂志》 >多西他赛联合心理干预对老年晚期非小细胞肺癌患者治疗中的应用价值分析

多西他赛联合心理干预对老年晚期非小细胞肺癌患者治疗中的应用价值分析

             

摘要

Objective To investigate the clinical value of docetaxel combined with psychological intervention in elderly patients with advanced non-small cell lung cancer. Methods the control group received docetaxel chemotherapy, and the study group received psychological intervention on the basis of docetaxel chemotherapy. The efficacy, adverse reactions and adverse emotions of two groups of elderly patients with advanced non-small cell lung cancer were recorded. Results the total efficiency was up to 54.17%, only 41.67% of the control group (P<0.05); toxic and side effects in the research group alopecia, gastrointestinal reaction, rash was significantly lower than the control group did not received psychological intervention (P<0.05); the control group after treatment SAS, SDS score increased than before more than the study group (P<0.05). Conclusion On the basis of docetaxel in the treatment of elderly patients with advanced non-small cell lung cancer, the use of appropriate psychological intervention measures can significantly alleviate the negative emotions, and have positive significance to ensure the effectiveness and safety of chemotherapy.%目的 探讨多西他赛联合心理干预对老年晚期非小细胞肺癌患者的临床应用价值.方法 对照组经多西他赛化疗治疗,研究组在多西他赛化疗基础上加用心理干预,比较2组老年晚期非小细胞肺癌疗效、不良反应及不良情绪.结果 研究组总有效率高达54.17%,对照组仅为41.67%(P<0.05);研究组脱发、胃肠道反应、皮疹等不良反应发生率显著低于未实施心理干预的对照组(P<0.05);经相应治疗后对照组SAS、SDS量表评分较之前提高幅度大于研究组(P<0.05).结论 在多西他赛治疗老年晚期非小细胞肺癌患者基础上加用相应心理干预措施可显著缓解其负面情绪,对确保化疗有效性、安全性均具有积极意义.

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