Objective To retrospectively analyze the clinical efficacy of simple endoscopic surgery and postoperative radiotherapy for esophageal cancer. Methods Kaplan-meier method and Cox regression model were used to analyze 101 cases of stage Ⅱa-Ⅲ esophageal cancer patients in 2011. Among them, 41 cases were treated with simple operation and 60 cases were treated with radiotherapy. The survival time and survival rate of the two groups were compared and analyzed Factors that affect their survival time. Results The median survival time was 31 months in the surgery group and 36 months in the radiotherapy group. The survival rate was 80%, 31%, 16% for 1, 3, and 5 years in the surgery alone group, 78%, 42% and 27% in the postoperative radiotherapy group, the overall survival rate was not statistically significant. The survival rate of patients with stage Ⅱb-Ⅲ was statistically significant (χ2= 4.02, P<0.05). Factors affecting the prognosis of esophageal squamous cell carcinoma and postoperative radiotherapy, tumor size, staging, smoking history. Conclusion There is no significant difference in the overall survival rate of esophageal squamous cell carcinoma between simple surgery and postoperative radiotherapy, but postoperative radiotherapy can improve the survival rate of patients with stage Ⅱb-Ⅲ.%目的 回顾性分析单纯腔镜根治手术与术后放疗对食管癌的临床疗效.方法 Kaplan-meier法和Cox回归模型分析2011年的Ⅱa~Ⅲ期食管癌患者101例,其中单纯手术者41例,术后放疗者60例,比较2组患者的生存时间、生存率,并分析影响其生存时间的因素.结果单纯手术组的中位生存时间为31个月,术后放疗组为36个月;单纯手术组的1、3、5年的生存率为80%、31%、16%,术后放疗组为78%、42%、27%,总生存率无统计学差异,Ⅱb~Ⅲ期患者的生存率差异有统计学意义(χ2=4.02,P<0.05).影响食道鳞癌预后的因素与术后是否放疗、肿瘤大小、分期、吸烟史相关.结论 单纯手术和术后放疗对食道鳞癌的总生存率没有显著性差异,但术后放疗能提高Ⅱb~Ⅲ期患者的生存率.
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