阿司匹林联合他汀类药物对脑血栓患者颈动脉斑块的改善作用

摘要

目的 探讨阿司匹林联合他汀类药物对脑血栓患者颈动脉斑块的改善作用.方法 选取宁波市康复医院2014年5月~2016年5月收治的脑血栓患者80例,依据治疗方法将这些患者分为2组,即单纯阿司匹林治疗组(单独治疗组,40例)和阿司匹林联合他汀类药物治疗组(联合治疗组,40例),对2组患者的NIHSS评分、Barthel指数、临床疗效、IMT、斑块面积进行统计分析.结果 联合治疗组患者的Barthel指数显著高于单独治疗组(P<0.05),NIHSS评分显著低于单独治疗组(P<0.05),治疗的总有效率95.0%(38/40)显著高于单独治疗组80.0%(32/40)(P<0.05),IMT显著短于单独治疗组(P<0.05),斑块面积显著小于单独治疗组(P<0.05).结论 阿司匹林联合他汀类药物较单纯阿司匹林更能有效改善脑血栓患者的颈动脉斑块状况,值得在临床推广使用.%Objective To investigate the improvement role of aspirin combined with statins on carotid plaque of patients with cerebral thrombosis.Methods80 cases of patients with cerebral thrombosis in our hospital from May 2014 to May 2016 were selected, these patients were divided into aspirin combined with statins treatment group (combined treatment group, 40 cases) and single aspirin treatment group (single treatment group, 40 cases) two groups according to the treatment methods, the NIHSS scores, Barthel indexes, clinical curative effects, IMT, plaque areas of the two groups were statistically analyzed.ResultsThe NIHSS score of the combined treatment group was significantly lower (P<0.05), the Barthel index was significantly higher (P<0.05), the total treatment efficiency 95.0% (38/40) was significantly higher than the single treatment group 80.0% (32/40) (P<0.05), the IMT was significantly shorter (P<0.05), the plaque area was significantly smaller than the single treatment group (P<0.05).ConclusionAspirin combined with statins can more effectively improve the carotid plaque of patients with cerebral thrombosis than aspirin alone, so is worthy of promotion and use in the clinical.