连续性血液净化对重症脓毒症患者的血乳酸及血流动力学的影响

摘要

Objective To explore the treatment of sepsis in patients with severe sepsis, the use of CBP (continuous blood purification) effect on lactic acid and hemodynamics in patients with blood.MethodsIn 40 cases of patients with severe sepsis treated by conventional methods, and classified as the control group, the other 40 patients using CBP (continuous blood purification treatment;blood lactic acid) after evaluation and hemodynamics of two groups of patients before and after treatment, and compared between groups, the patients were treated in our hospital from January 2015 to October 2016.ResultsThere was no significant difference in blood lactate level of the two groups of patients before treatment, after grouping After treatment, the patients in the observation group decreased more significantly, while the monitoring of patients in different time period, showed its obvious difference;hemodynamics of two groups were observed and compared, found before treatment all indexes had no significant difference after the treatment group were improved more obviously in patients in the observation group, group are P<0.05 shows obvious differences.ConclusionAnalysis of the influence of the dynamics of CBP in severe sepsis patients blood lactic acid and blood flow, which can significantly improve the patient's level of lactic acid, which decreased gradually, while helping the hemodynamic situation of the patient to recover, it is worthy of reference.%目的 探究重症脓毒症患者治疗时,使用连续性血液净化(CBP)对于患者血乳酸及血流动力学的影响.方法 针对40例重症脓毒症患者采用常规方法治疗,同时归为对照组,针对另外40例患者使用CBP治疗;此后评价2组患者治疗前后的血乳酸及血流动力学情况,并在组间进行比较分析,入选患者均为暨南大学附属第一医院2015年1月~2016年10月间收治.结果 2组患者的血乳酸水平在治疗前无明显差异,经过分组治疗后,观察组患者下降更加明显,同时在不同时间段对患者进行监测,均可见其明显差异;观察并比较2组患者的血流动力学情况,发现其在治疗前各项指标均无明显差异,经过分组治疗后均为观察组患者改善更加明显,组间均为P<0.05则说明差异明显.结论 CBP对重症脓毒症患者的血乳酸及血流动力学的影响分析发现,其能够显著改善患者体内的乳酸水平,使其逐渐下降,同时帮助患者的血流动力学情况得以恢复,因此值得临床借鉴.