抗肿瘤干细胞活性物质研究进展

摘要

Cancer stem cells play a crucial role in tumors'invasion, metastasis, recurrence and drug resistance.Investigation on the chemicals with tumor stem cell growth inhibitory activity has been greatly highlighted in the field of anti-tumor drug discovery.This paper briefly reviews the recent progress of chemical investigations on substances with tumor stem cell growth inhibitory activity , aiming to give readers a reference on anti-tumor drug discovery.%肿瘤干细胞是肿瘤侵袭、转移、复发及耐药的关键因素,寻找新型抗肿瘤干细胞药用活性物质已经成为抗肿瘤药物研究的热点.本文对近来抗肿瘤干细胞活性物质研究进展进行了综述,以期为抗肿瘤活性物质研究提供参考.