反刍动物瘤胃挥发性脂肪酸的吸收机制

摘要

瘤胃发酵碳水化合物产生挥发性脂肪酸(VFA),其在瘤胃上皮通过被动扩散、挥发性脂肪酸酸根离子(VFA-)和碳酸氢根(HCO-3)的阴离子交换、硝酸盐敏感性VFA吸收、质子耦合VFA-运输以及电介导途径转运,为反刍动物提供能量;同时VFA会刺激瘤胃上皮发生适应性变化,促进瘤胃乳头生长和增加瘤胃上皮VFA吸收相关的基因表达.本文对VFA在瘤胃上皮的吸收转运机制及瘤胃上皮VFA吸收相关基因进行综述,旨在为进一步研究瘤胃的营养调控提供理论基础.%Volatile fatty acids ( VFAs) produced by ruminal fermentation of dietary carbohydrates are translo-cated through the following pathways in ruminants: passive diffusion in rumen epithelium, acid radical ion of VFAs ( VFA-)/HCO-3 anion exchange, nitrate-sensitive VFAs absorption, proton-coupled VFA-transport and electron mediating mechanisms. At the same time, VFAs stimulate the rumen epithelium adaptive changes to promote rumen papillae growth and increase gene expressions associated with rumen epithelial VFA absorption. This article summarized the mechanism of VFA absorption and transport through the ruminal epithelium, and the gene expressions related to rumen epithelial VFA absorption, aiming to provide a theoretical basis for fur-ther investigation on nutritional regulation of rumen.