饲粮添加三丁酸甘油酯和核苷酸对断奶仔猪生长性能、血清生化指标和肠组织形态的影响

摘要

本试验旨在研究饲粮添加三丁酸甘油酯和核苷酸对仔猪生长性能、血清生化指标和肠组织形态的影响.选择21日龄、体重为8.4 kg左右的健康杜洛克×长白×大约克(DLY)三元断奶仔猪160头,随机分为2组,每组10个重复,每个重复8头.对照组饲喂基础饲粮,试验组饲喂在基础饲粮中添加0.20％三丁酸甘油酯和0.15％核苷酸的试验饲粮,试验期为38 d.结果表明:1)与对照组相比,饲粮添加三丁酸甘油酯和核苷酸显著提高了断奶仔猪的平均日增重(P＜0.05),极显著降低了腹泻率(P＜0.01),显著提高了血清免疫球蛋白A、免疫球蛋白G、免疫球蛋白M以及球蛋白含量(P＜0.05),显著降低了血清二胺氧化酶活性和葡萄糖含量(P＜0.05);2)与对照组相比,饲粮添加三丁酸甘油酯和核苷酸显著提高了断奶仔猪十二指肠和空肠绒毛高度和绒毛高度/隐窝深度值(P＜0.05),显著提高了空肠内容物胰蛋白酶和麦芽糖酶活性(P＜0.05).由此可见,饲粮添加0.20％三丁酸甘油酯和0.15％核苷酸可促进仔猪生长,提高机体免疫力,降低断奶应激对肠道的损伤,提高消化酶活性,改善仔猪的消化吸收功能.%This experiment was conducted to investigate the effects of dietary tributyrin and nucleotide on growth performance,serum biochemical indices and intestinal morphology of weaned piglets.One hundred and sixty 21-day-old healthy Duroc×Landrace×Yorkshire piglets with about 8.4 kg body weight were randomly allotted into two groups with 10 replicates each and 8 pigs in each replicate.The piglets in the control group were fed a basal diet and in the experimental group were fed the basal diet supplemented with 0.20％ tributyrin and 0.15％ nucleotide,and the trial lasted for 38 days.The results showed as follows:1) compared with the control group,dietary tributyrin and nucleotide significantly increased the average daily gain (P＜0.05),extremely significantly decreased the diarrhea rate (P＜0.01),significantly increased the contents of immunoglobulin A,immunoglobulin G,immunoglobulin M and globulin in serum (P＜0.05),and significantly decreased the diamine oxidase activity and glucose content in serum (P＜0.05) of weaned piglets.2) Compared with the control group,dietary tributyrin and nucleotide significantly increased villus height and the ratio of villus height to crypt depth in duodenum and jejunum (P＜0.05),and significantly increased the activities of trypsin and maltase in jejunum contents (P＜0.05) of weaned piglets.Thus,it can be seen that dietary tributyrin and nucleotide can improve the growth performance,enhance immunity of organism,reduce the damage of weaning stress to the intestine,increase digestive enzyme activity,and enhance digestion-absorption function of weaned piglets.