目的 探讨睾丸间质细胞瘤的诊断和治疗经验.方法 报告1例双侧睾丸间质细胞瘤患者的临床资料并文献复习.结果 根据患者临床表现及相关检查,术前诊断考虑为双侧睾丸间质细胞瘤,术中快速冰冻病理检查示双侧睾丸间质细胞瘤,行睾丸肿瘤剜除术.术后随访6个月未见肿瘤复发或转移.结论 睾丸间质细胞瘤是一种较为罕见的睾丸肿瘤.术前诊断较为困难,睾酮、雌二醇等性激素水平升高及男性乳房发育等症状对睾丸间质细胞瘤的诊断有重要意义,确诊仍需依赖病理组织学检查.传统的手术方法采用根治性睾丸切除术,然而对于青春期前患者、双侧睾丸间质细胞瘤等患者,可以施行保留睾丸的肿瘤剜除术.%Objective To summarize and analyze the diagnosis and treatment of Leydig cell tumor. Methods One case of bilateral Leydig cell tumor of testis was reported and related literatures were reviewed. Results The patient was diagnosed as Leydig cell tumor based on clinical characteristics and examination Leydig cell tumor of testis was confirmed by frozen section pathological analysis during the operation. The patient underwent testicular tumor enucleation. No local recurrence or distant metastasis was detected during 6 months follow-up. Conclusion Leydig cell tumor was a rare type of male testicular tumor. Diagnosis of this disease depended on pathological analysis. Traditional surgical method was radical orchiectomy. But for pre-adolescent patients with bilateral testicular Leydig cell tumor or single testis, especially their pathological grade was benign, tumor enucleation was a feasible and safe choice.
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