小鼠胚胎肾细胞凋亡与胀亡的超微结构

摘要

Objective: To observe the ultrastructures of apoptosis and oncosts in embryonic mouse kidneys. Methods: Transmission electron microscope was used in this study. Results: Oncosis could be found as a programmed cell death in embryonic mouse kidneys. However it was less obvious than apoptosis. Cytoplasm swelling of oncosis was the principal difference from apoptosis which had condensed cytoplasm. Conclusion: Apoptosis is more principle as programmed cell death than oncosis during kidney development.%目的:观察小鼠胚胎肾发育中细胞凋亡与胀亡的超微结构.方法:应用透射电子显微镜对不同胚龄大鼠肾进行了系统观察.结果:作为细胞程序性死亡的胀亡出现在发育的肾中,但与凋亡相比出现的频率不高.凋亡与胀亡的不同仅在于细胞质的表现.结论:在肾发育中细胞凋亡仍然为主要的程序性细胞死亡,胀亡只处于辅助地位.