姜黄消痤搽剂联合座疮涂膜剂治疗寻常性痤疮疗效观察

摘要

Objective To evaluate the clinical efficacy and safety of the combination therapy of Jianghuang Xiaocuo liniment with Cuochuang plaster in patients with acne vulgaris. Methods 150 cases are randomly divided into three groups, Combined therapy group received Jianghuang Xiaocuo liniment(twice a day) plus Cuochuang plaster(once daily in the evening),the control Ⅰ group received Jianghuang Xiaocuo liniment (twice a day),and the control Ⅱ group received Cuochuang plaster (once daily in the evening).All patients were followed-up and observed before treatment, during in the treatment of time 4 and 8weeks,2 months after stopping treatment. Results After 8 weeks of treatment, the effectiveness were better in Combined therapy group than in the control groups (P＜0.05),and no serious adverse reactions were found. Conclusion It is effective and safe of Jianghuang Xiaocuo liniment combined with Cuochuang plaster treatment of acne vulgaris.%目的:评价姜黄消痤搽剂联合痤疮涂膜剂治疗寻常性痤疮的疗效与安全性.方法:将150例痤疮患者随机分为三组:试验组:白天外用姜黄消痤搽剂,2次/天,晚上睡前外用痤疮涂膜剂,1次/天;对照Ⅰ组:白天外用姜黄消痤搽剂,2次/天;对照Ⅱ组:晚上睡前外用痤疮涂膜剂,1次/天.在治疗前、治疗第4周、8周时及停止治疗后2个月观察疗效.结果:治疗8周后,姜黄消痤搽剂和痤疮涂膜剂试验组有效率(83.33%)与姜黄消痤搽剂组(61.22%)及痤疮涂膜剂组(64.58%)相比,差异有统计学意义(均P<0.05),且不良反应少.结论:姜黄消痤搽剂联合痤疮涂膜剂治疗寻常性痤疮安全,疗效满意.