单用强脉冲光、长脉宽Nd:YAG激光以及低能量下两者联合使用治疗微静脉畸形的临床疗效比较

摘要

目的:观察单用强脉冲光、长脉宽1064nm Nd:YAG激光以及低能量下两者联合使用治疗微静脉畸形的临床疗效和不良反应.方法:联合应用590～ 1200nm强脉冲光(能量密度12 ～ 16J/cm2,脉宽3.0 ～ 5.0ms)以及长脉宽1064nm Nd:YAG激光(能量密度80 ～ 90J/cm2,脉宽10～ 20ms)治疗51例微静脉畸形患者；并与单独应用强脉冲光(能量密度13～ 20J/cm2)及长脉宽Nd∶ YAG激光(能量密度120 ～ 145J/cm2)治疗结果比较.结果:强脉冲光、长脉宽1064nmNd:YAG激光及低能量下联合使用治疗微静脉畸形的有效率分别为33.1％、40.3％和56.9％,瘢痕发生率分别为0％、10.7％和5.9％.结论:低能量下联合使用强脉冲光及长脉宽1064nm Nd:YAG激光提高了微静脉畸形的有效率,且不良反应小.%Objective To investigate the clinical efficacy and adverse effect of intense pulsed light(IPL),long-pulse 1064nm Nd:YAG laser and combined therapy with low energy for the treatment of venular malformation.Methods Fifty-one patients with venular malformation were treated by combined therapy (590～1200 nm IPL and long-pulse 1064nm Nd:YAG laser).The treatment parameters of IPL were as follows∶12～16 J/cm2 energy density,3.0～5.0ms pulse duration.The treatment parameters of Nd∶YAG laser∶ 80～90 J/cm2 energy density,10～20ms pulse duration.The clinical efficacy and side effect of IPL and Nd:YAG laser were also observed separately.Results The effective rates were 33.1％,40.3％ and 56.9％ in venular malformation treated only with IPL,Nd:YAG laser and combined therapy respectively.While the incidences of scar were 0％,10.7％ and 5.9％ respectively.Conclusion IPL combined with long-pulse 1064nm Nd∶YAG laser in low energy is more effective and less adverse effect in the treatment of venular malformation.