Tei指数用于初步估测冠状动脉狭窄程度的临床研究

摘要

Objective: To assess coronary stenosis scope preliminarily by applying TDI Tei index. Methods:Determined the left ventricular Tei index by tissue doppler imaging (TDI)technique of the 30 normal subjects ,30 patients with negative results of coronary arteriography (stenosis<50% ) ,30 patients with mild coronary stenosis (stenosis 50% -74% )and 30 patients with moderate coronary stenosis (stenosis 75% -94% ). Results:The left ventricular Tei index in mild and moderate coronary stenosis patient was obviously higher than in the normal subject (P<0. 05),but there is no statistic significance in the difference between normal subject and patient with negative results of coronary arteriography. There was significant correlation between coronary stenosis and Tei index(r=0. 944). Conclusion:The value of Tei index could be applied to assess the stenosis scope of the coronary artery.%目的:检测经冠脉造影确定冠脉狭窄程度患者的Tei指数,并进行统计学分析,探讨其用于估测冠状动脉狭窄程度的临床价值.方法:采用组织多普勒显像技术测量30例正常对照组、30例冠状动脉造影阴性组(狭窄程度＜50%)、30例轻度冠状动脉狭窄组(狭窄程度50%～74%)和30例中度冠状动脉病变组(狭窄程度75%～94%)的左心室Tei指数.运用统计学方法,分析Tei值与冠脉狭窄程度之间的相关关系.结果:冠状动脉造影阴性组Tei指数与正常对照组比较差异无统计学意义,轻度、中度冠状动脉狭窄组Tei指数显著高于正常对照组(P＜0.05);Tei指数与冠脉病变程度呈正相关(r=0.944).结论:Tei值与冠状动脉狭窄程度存在明显的相关性,可用于初步估测冠状动脉狭窄的程度.