Synthesis of O-benzyl oximes by combination of phase transfer catalysis and ultrasound irradiation

摘要

The reactions of oximes with benzyl bromide catalyzed by benzyldimethyltetradecylammonium chloride are carried out at room temperature for 30-60 min in aqueous sodium hydroxide solution under ultrasound irradiation to offer O-benzyl oxime derivatives in 60-96% yields. In comparison to classical methods, the advantages of the present procedure include short reaction time, high yields and environmental friendliness.