急性脑卒中院内死亡相关危险因素的临床研究

摘要

Objective To investigate the risk factors for intrahospital death of patients with acute stroke with the expect to aid treatment of the disease and to reduce intrahospital mortality.Methods A total of 1 500 patients with acute stroke ever treated by our hospital were retrospectively reviewed with risk factors for intrahospital death analysed.Results Intrahospital mortality rate for patients with acute stroke was 3％ ( 45/1 500 ).Risk factors include age , coma status, hyperpyrexia, pulmonary infections.brain - heart syndrome , history of stroke , midline shift , serum glucose levels.blood pressure.serum sodium, levels , serum potassium levels and gastrointestinal bleeding ( P ＜ 0.05 ～ 0.01 ) Among them, coma status, hyperpyrexia, pulmonary infections.brain - heart syndrome, midline shift , and gastrointestinal bleeding were closely related to the mortality of acute stroke ( P ＜ 0.01 ).Conclusion Coma status, hyperpyrexia, pulmonary infections.brain - heart syndrome.midline shift and gastrointestinal bleeding are the most close risk factors for intrahospital death among patients with acute stroke.%目的探讨急性脑卒中患者的院内病死率及其相关危险因素,指导临床治疗,降低其病死率.方法收集我院1 500例急性脑卒中患者的临床资料,对引起死亡的多种危险因素进行分析.结果急性脑卒中患者院内病死率为3%(45/1 500).年龄、昏迷、高热、肺部感染、脑中线移位、消化道出血、脑心综合征、卒中史、留置胃管和尿管及血压、血糖、心肌肌酸激酶同工酶、血钾、血钠、血肌酐、血尿素氮水平与患者的死亡关系密切(P＜0.05～0.01),尤其是昏迷、高热、肺部感染、脑心综合征、脑中线移位、消化道出血与急性脑卒中患者的死亡关系最为密切(P＜0.01).结论昏迷、高热、肺部感染、脑心综合征、脑中线移位、消化道出血是急性脑卒中患者院内死亡的重要危险因素.