妊娠期尿路感染危险因素的临床研究

摘要

目的 探讨妊娠期尿路感染的危险因素.方法 选取2008年1月-2012年1月在我院就诊有尿路刺激症状的妊娠期妇女为研究对象.根据是否发生妊娠期尿路感染分为尿路感染组和非尿路感染组.首先,单因素分析比较两组年龄、受教育程度、妊娠期性生活史、家庭人均收入、尿路感染史、生育次数及血红蛋白等危险因素的差别.然后,以是否发生尿路感染为因变量,以单因素分析有统计学意义的变量为自变量,进行Logistic回归分析,进一步探讨妊娠期尿路感染的危险因素.结果 (1)尿路感染组尿路感染史、妊娠期性生活史及贫血比例高于非尿路感染组,差异有统计学意义(P＜0.05)；尿路感染组受教育程度低于非尿路感染组,差异亦有统计学意义(P＜0.05).(2)Logistic回归分析显示,有尿路感染史患者发生妊娠期尿路感染风险是无尿路感染史者的1.232倍[95％CI (1.183,1.424),P=0.030]；血红蛋白＜110 g/L患者发生妊娠期尿路感染风险是血红蛋白≥110g/L者的1.152倍[95％ CI(1.091,1.471),P=0.043]；妊娠期有性生活史者发生妊娠期尿路感染风险是无性生活史者的1.133倍[95％ CI(1.011,1.576),P=0.028].结论 泌尿系感染史、贫血和妊娠期性生活是妊娠期尿路感染的独立危险因素.%Objective To explore the risk factors for urinary tract infection (UTI) in pregnancy. Methods A total of 368 pregnant women in our hospital between January 2008 and January 2012 who exhibited urinary irritation symptoms were included in the study. They were divided into a UTI group and a control group based on the presence of UTI. The age, education level, family income per capita, history of sexual activity during pregnancy, UTI history, parity, and hemoglobin level of the subjects were compared using univariate analysis. Logistic regression analysis was used to explore the risk factors for UTI. Results The proportion of patients in UTI group with history of sexual activity during pregnancy, history of UTI, anemia was significantly higher than that in the control group ( P < 0. 05 ) ; and the paitents with lower education level had higher risk of developing UTI than those with higher education level (P < 0. 05 ) .By Logistic regression analysis, subjects with history of sexual activity during pregnancy (95% CI (1.011, 1.576), P = 0.028], history of UTI (95%CI (1.183, 1.424), P=0.030], or anemia [95% CI (1.091, 1.471), P = 0.043] had higher risk of developing UTI during pregnancy. Conclusion History of UTI, history of sexual activity during pregnancy, and anemia were independent risk factors for UTI in pregnancy.