年龄相关性黄斑变性的发病机制及治疗研究现状

摘要

Age - related macular degeneration(AMD)is the primary cause of the blindness of the elderly. Among the population aged more than 50 years old,the prevalence of AMD increases with age growing. With the advent of aging society,the number of people with AMD is increasing year by year. Although in recent years the researchers have done a lot of basic and clinical research on the pathogenesis and treatment method of AMD,its pathogenesis remains controversial and there are no ideal treatment methods. This paper made a review about the pathogenesis and treatment methods of AMD in recent years and pointed out that the occurrence and development of AMD are very complex and many regulatory factors and cells are involved. However,more research should be conducted to confirm the pathogenesis and treatment methods.%年龄相关性黄斑变性（AMD）是老年人的首要致盲疾病。50岁以上人群中，随着年龄增长发病率增加。随着我国老龄化社会的到来，发病人数逐年增加。尽管最近几年研究人员对 AMD 的发病机制、治疗方法做了大量基础研究及临床研究，但由于该疾病本身的复杂性，其发病机制仍存在争议，同时也无理想的治疗方式。本文就近几年 AMD 的发病机制及治疗方法进行综述，指出 AMD 的发生和发展是一个极其复杂的过程，大量的调节因子及细胞因子参与其中，对于 AMD 的发病机制及治疗方法仍需大量研究加以证实。