首页> 中文期刊>中国全科医学 >天津地区不同性别与年龄老年人肌肉减少症患病率的差异研究

天津地区不同性别与年龄老年人肌肉减少症患病率的差异研究

摘要

Objective To explore the gender and age differences in the prevalence rate of sarcopenia in the elderly in Tianjin area.Methods From December 2014 to August 2016,a total of 6 033 cases were selected as the research objects included the elderly (age≥60 years old,n =3 276) consulted and/or physically examined in outpatient department of Tianjin First Central Hospital and recruited healthy volunteers (aged 18 to 59 years,n =2 757).The subjects were investigated by a self -designed questionnaire,mainly including gender,age,and chronic medical history.Body composition was measured by bioelectrical impedance analysis (BIA),and bodv mass index (BMI),fat mass,skeletal muscle mass and muscle mass index were recorded.Muscle strength was measured by grip strength,measured each hand 2 times,and the highest value was obtained.Muscle function was determined by walking 4 m velocity.Results According to the diagnostic criteria for sarcopenia of Asian Working Group for Sarcopenia (AWGS),the sarcopenia prevalence rate of elderly was 12.82% (420/3 276).Among them,the prevalence rate of male was 11.10% (258/2 325),and prevalence rate of the female was 17.03% (162/951).In 60-69 and 70-79 years old women,the prevalence rate of sarcopenia was higher than male (P < O.05).With the increase of age,the prevalence rate of sarcopenia in different gender increased (P < 0.05).There were significant differences in BMI among all age groups in female (P < 0.05).The BMI in 18-44,45-59,60-69 years old male were higher than female (P <0.05).There were significant differences in fat mass,skeletal muscle mass and muscle mass index among all age groups in male and female (P < 0.05).The skeletal muscle mass and muscle mass index of all age groups in male were higher than female (P < 0.05).There were significant differences in grip strength in all age groups of male and female (P < 0.05).The grip strength of all age groups of male were higher than female (P <0.05).The walking velocity in male was higher than female in 70 -79 years old group (P < 0.05).The detection rate of coronary heart disease and sequelae of cerebral infarction in male and female sarcopenia patients were higher than those in people without sarcopenia (P < 0.05).Conclusion There are gender and age differences in the occurrence of sarcopenia in the elderly.With increase of age,the prevalence rate of sarcopenia increased,and the prevalence rate of female is higher than male.%目的 探讨天津地区老年人肌肉减少症患病率的性别、年龄差异.方法 选取2014年12月-2016年8月于天津市第一中心医院门诊就诊、查体老年人(年龄≥60岁,n=3 276),以及招募的健康志愿者(年龄18~ 59岁,n =2 757)共6 033例为研究对象通过自制的调查问卷调查受试者基本情况,主要内容包括性别、年龄、慢性病病史.采用生物电阻抗分析(BIA)法测量人体成分,记录体质指数(BMI)、脂质量、骨骼肌质量、肌肉质量指数.肌肉力量由握力测定,每只手测量2次,取最高值肌肉功能由行走4 m步速测定.结果 根据亚洲肌肉减少症工作组(AWGS)肌肉减少症的诊断标准,老年人肌肉减少症患病率为12.82% (420/3 276),其中,老年男性、女性肌肉减少症患病率分别为11.10% (258/2 325)、17.03% (162/951). 60 ~69岁、70 ~79岁女性肌肉减少症患病率高于男性(P<0.05).不同性别老年人均随着年龄的增加,肌肉减少症患病率增加(P<0.05).女性各年龄段BMI比较,差异有统计学意义(P <0.05) 18 ~44岁、45 ~59岁、60 ~69岁男性BMI高于女性(P<0.05).男性、女性各年龄段脂质量、骨骼肌质量、肌肉质量指数比较,差异均有统计学意义(P<0.05).各年龄段男性骨骼肌质量、肌肉质量指数均高于女性(P<0.05).男性、女性各年龄段握力比较,差异均有统计学意义(P<0.05).各年龄段男性握力均高于女性(P<0.05),70 ~79岁男性步速大于女性(P<0.05) . 男性、女性肌肉减少症患者冠心病、脑梗死后遗症检出率高于无肌肉减少症者(P<0.05).结论 老年人肌肉减少症的发生存在性别、年龄差异,随着年龄的增加,肌肉减少症患病率增加,且女性患病率高于男性.

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