维持性血液透析高血压及其治疗进展

摘要

高血压是维持性血液透析（MHD）常见并发症之一，严重影响患者的生存质量和长期生存率。MHD高血压的发生可能与容量负荷增加、肾素-血管紧张素系统（RAS）激活、交感神经系统活化等有关，维持理想干体质量与合理应用降压药为现阶段主要治疗策略。近年来，研究人员对 MHD 高血压提出了新的治疗方案。本文就 MHD高血压的临床特征、发病机制、治疗进展进行综述，以期为 MHD 高血压的诊治提供参考。%Hypertension is one of the most common complications in maintenance hemodialysis( MHD),which seriously affected the quality of life and long - term survival rate of patients. The probable mechanism of MHD - associated hypertension includes extracellular fluid volume expansion,renin - angiotensin system activation,sympathetic nervous system activity,and so on. Maintaining ideal dry weight and properly using antihypertension drugs are the mainly therapies for MHD -associated hypertension at present. In recent years,some new therapies have been proposed to treat the MHD - associated hypertension patients. This review summarized the clinical features, pathogenesis and therapies of MHD - associated hypertension,hoping to provide references for its diagnosis and treatment.